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HERO ID
3981934
Reference Type
Journal Article
Title
Rapid determination of small molecule pollutants using metal-organic frameworks as adsorbent and matrix of MALDI-TOF-MS
Author(s)
Wang, S; Niu, H; Zeng, Tao; Zhang, X; Cao, D; Cai, Y
Year
2017
Is Peer Reviewed?
1
Journal
Microporous and Mesoporous Materials
ISSN:
1387-1811
Publisher
Elsevier B.V.
Location
AMSTERDAM
Volume
239
Page Numbers
390-395
Language
English
DOI
10.1016/j.micromeso.2016.10.032
Web of Science Id
WOS:000389284300044
Abstract
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) has been commonly used for the determination of macromolecules owing to the high sensitivity and convenience. However, the direct analysis of small molecule with MALDI-TOF-MS remains a challenge due to the matrix interference in the low mass region. In this paper, metal-organic frameworks (MOFs: MOF-5, MOF-235, Cu-btc MOFs and Uio-66(Zr)-2OH) were successfully used as both adsorbent and significant matrix of MALDI-TOF-MS method for the analysis of small molecule pollutants. Benzo(a)pyrene (BaP) and perfluorinated compounds (PFCs) were chosen as model analytes to investigate the matrix function of MOFs with LDI measurement in positive and negative reflection mode, respectively. As a result, MOFs exhibit high laser desorption/ionization efficiency and function well in both positive-ion and negative ion modes. Compared to the MS spectra with conventional matrices, MS spectra obtained on MOFs matrix are only featured by deprotonated molecule ion peaks without background interference. Furthermore, MOFs, with large surface area and pi-pi stacking structure, can also enrich trace amounts of small molecule pollutants from solution efficiently and quickly. According to these, we developed a simple method in which MOFs-solid-phase extraction (SPE) enrichment was combined with MALDI-TOF-MS to realize the direct analysis of perfluorooctanesulfonate (PFOS) in real water samples. (C) 2016 Elsevier Inc. All rights reserved.
Keywords
Metal-organic framework; MALDI-TOF-MS; PFOS; Matrix; Enrichment
Tags
PFAS
•
^Per- and Polyfluoroalkyl Substances (PFAS)
PFOA (335-67-1) and PFOS (1763-23-1)
Literature Search – Adverse outcome pathway (2015-present)
WOS
•
PFAS Universe
Data Source
Web of Science
Perfluorooctanesulfonate
Perfluorooctanesulfonic acid
OW - HHRAB
•
PFOA (335-67-1) and PFOS (1763-23-1)
Literature Search – Adverse outcome pathway (2015-present)
WOS
Screening Results
Excluded/Not on Topic
Literature Search Update (2013-2019)
WOS
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