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Citation
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HERO ID
682040
Reference Type
Journal Article
Title
Inhibition of 15-lipoxygenase by phthalate plasticizers
Author(s)
Malterud, KE; Rydland, KM; Haugli, T
Year
1999
Is Peer Reviewed?
Yes
Journal
Bulletin of Environmental Contamination and Toxicology
ISSN:
0007-4861
EISSN:
1432-0800
Volume
62
Issue
3
Page Numbers
352-355
Language
English
PMID
10085180
DOI
10.1007/s001289900881
Web of Science Id
WOS:000079136500017
Abstract
Somewhat serendipitously, we observed that 15-lipoxygenase (15-LO) inhibition by a plant extract was in part due to the presence of di-(2-ethylhexyl) phthalate as a contaminant. Since modulation of lipoxygenase activity by phthalate esters does not appear to be well known, we decided to study this effect further. The results are reported in this communication.
Keywords
antagonists & inhibitors; Arachidonate 15-Lipoxygenase; Dibutyl Phthalate; Diethylhexyl Phthalate; Enzyme Inhibitors; metabolism; pharmacology; Phthalic Acids; Plasticizers
Tags
•
Dibutyl Phthalate (DBP)
Database Searches
Pubmed
LitSearch Nov 2012
PubMed
Merged reference set
Excluded: No Primary Data on Health Effects
Not chemical specific
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