US EPA

758837 

Journal Article 

Identification of organic compounds in a mutagenic extract of a surface drinking water by a computerized gas chromatography/mass spectrometry system (GC/MS/COM) 

Coleman, WE; Melton, RG; Kopfler, FC; Barone, KA; Aurand, TA; Jellison, MG 

1980 

1 

Environmental Science & Technology
ISSN: 0013-936X
EISSN: 1520-5851 

HEEP/80/13211 

14 

5 

576-588 

10.1021/es60165a012 

http://pubs.acs.org/doi/abs/10.1021/es60165a012
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HEEP COPYRIGHT: BIOL ABS. The organics in a Cincinnati, Ohio (USA) drinking water sample were concentrated by a reverse osmosis (RO) process. The diethyl ether soluble extract of the RO concentrate, which was mutagenic in studies using the Ames test (using Salmonella typhimurium), was partitioned into acid and base/neutral fractions. The unpartitioned ethyl ether concentrate, an acid and methylated acid fraction, the unpartitioned base/neutral extract, and 5 base/neutral eluants from a silica gel microcolumn were analzyed for the presence of organics using a computerized gas chromatography/mass spectrometry system (GC/COM) equipped with glass capilalry columns. Analysis of individual fractions indicated a predominance of polychlorinated biphenyls (PCB) and chlorinated aromatics in the 2nd base/neutral partition and many polynuclear aromatics (PNA) in the 4th base/neutral partition. Approximately 460 compounds were identified in this tap water extract, including 41 PNA, 15 PCB and a number of amines, amides and other halogenated species. (Human applicability is discussed. Some of the water impurities may be carcinogenic)./ANATOMY and HISTOLOGY