Journal Article
Persistent organic pollutants and heavy metals in adipose tissues of patients with uterine leiomyomas and the association of these pollutants with seafood diet, BMI, and age
Qin, Y; Leung, C; Leung, A; Wu, SC; Zheng, J; Wong, MH
Environmental Science and Pollution Research
ISSN: 0944-1344
EISSN: 1614-7499
Ecomed Verlagsgesellschaft AG & Co. KG, Justus-von-Liebig-Strasse 1 Landsberg D-86899 Germany
Background, aim, and scope: Persistent organic pollutants and heavy metals can cause diseases in women, however, the relationships of these pollutants and uterine leiomyomas (UL), which are non-cancerous tumors of the uterus, are unclear. This study focused on the quantification of organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), polybrominated diphenyl ethers (PBDEs), and heavy metals in subcutaneous and visceral fat obtained from patients with UL and in subcutaneous fat of a control group of women without UL to determine if there were any correlations between concentrations of persistent organic pollutants (POPs) and heavy metals and the incidence of UL. Materials and methods: Samples were collected from ethnic Chinese residents from six hospitals and six cosmetic surgery clinics in Hong Kong. Patients with UL provided both subcutaneous and visceral fat, while women without UL (control group) provided subcutaneous fat through liposuction. Analyses of POPs and heavy metals were conducted using gas chromatography-mass spectrometry and inductively coupled plasma-optical emission spectrometry, respectively. Total mercury (Hg) content was measured using an atomic fluorescence spectrometer. Results: Significantly higher (p
China, People's Rep., Hong Kong; Water Pollution Effects; Insecticides; Estrogen; Fish; Aromatic hydrocarbons; Surgery; polybrominated diphenyl ethers; Hospitals; estrogens; Mercury; Lead; Diets; heavy metals; Polycyclic aromatic hydrocarbons; DDT; Metabolites; PCB; Arsenic; Pollutants; body mass; Diet; Polychlorinated Biphenyls; Chemicals; Cadmium; Sex hormones; Bioaccumulation; Women; Thunnus; Fluorescence; PCB compounds; Seafood; hexachlorocyclohexane; Analysis; Patients; Pollutant persistence; persistent organic pollutants; Age; Pollution
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH