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HERO ID
1797774
Reference Type
Journal Article
Subtype
Review
Title
Use of OMIC technologies to study arsenic exposure in human populations
Author(s)
Moore, LE; Karami, S; Steinmaus, C; Cantor, KP
Year
2013
Is Peer Reviewed?
Yes
Journal
Environmental and Molecular Mutagenesis
ISSN:
0893-6692
EISSN:
1098-2280
Volume
54
Issue
7
Page Numbers
589-595
Language
English
PMID
23893652
DOI
10.1002/em.21792
Web of Science Id
WOS:000323124300012
Abstract
Exposure to arsenic (As) in drinking water is a major health concern. More than 100 million individuals are exposed to levels over the current World Health Organization standard of 10 µg/L worldwide. Arsenic is one of the few agents established as a human carcinogen prior to understanding its mechanism of carcinogenicity. OMIC technologies have enabled researchers to utilize agnostic approaches to explore new, unknown mechanisms through which As causes disease in exposed human populations. In this article, we present recent studies in which OMIC technologies have been used to explore differences in human biological samples to identify markers of exposure, disease susceptibility, and effect in As-exposed and/or diseased tissues. Environ. Mol. Mutagen., 2013. © 2013 Wiley Periodicals, Inc.
Keywords
arsenic; OMICS; epigenetics; transciptonics proteomics
Tags
•
Arsenic Hazard ID
PubMed
Considered New
PubMed
ToxNet
Considered New
WOS
ToxNet
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Toxnet Duplicates
ToxNet
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Toxnet Duplicates
ToxNet
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Reviews
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ToxNet
Excluded
Reviews
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2. Lit Search Updates through Oct 2015
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7. Other Studies through Oct 2015
Review/Risk Assessment/Guidance document
•
Arsenic (Inorganic)
1. Literature
Lit search updates through Oct 2015
•
Arsenic Susceptibility
1. Susceptibility Literature Screening
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2. Excluded
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Top 5%
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