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3859276 
Journal Article 
Biotransformation of 6:2 polyfluoroalkyl phosphates (6:2 PAPs): Effects of degradative bacteria and co-substrates 
Lewis, M; Kim, MH; Liu, EJ; Wang, N; Chu, KH 
2016 
Yes 
Journal of Hazardous Materials
ISSN: 0304-3894
EISSN: 1873-3336 
320 
479-486 
English 
Polyfluoroalkyl phosphates (PAPs), a group of fluorotelomer alcohol (FTOH)-based surfactants commonly used in water- and grease-proof food contact paper, have been suggested as a direct source of human exposure to health-concerned perfluoroalkyl carboxylic acids (PFCAs). This study investigated factors affecting biotranformation of 6:2 polyfluoroalkyl phosphates (6:2 PAPs) by three known FTOH-degrading Pseudomonas strains (Pseudomonas butanovora, P. oleovorans, and P. fluorescens DSM 8341) under different co-substrate conditions and compared to that by activated sludge samples. The three pure strains transformed 6:2 PAPs into eight different per- and poly-fluoroalkyl carboxylic acids (PFCAs) and/or PFCA precursors. P. fluorescens DSM 8341 produced 5:2 sFTOH [CF3(CF2)4CH(OH)CH3] and P. oleovorans produced 5:2 ketone [CF3(CF2)4C(O)CH3] as the primary transformation product, respectively, with citrate having a minimal impact on the transformation. P. butanovora with lactate produced more diverse transformation products than those by any two strains. Activated sludge was more efficient at transforming 6:2 PAPs and produced more transformation products including PFHpA [CF3(CF2)5COOH] and PFPeA [CF3(CF2)3COOH], with 5:2 sFTOH as the most abundant product on day 30. The abundance of the alkane hydroxylase (alkB) gene related to alkane oxidation, the changes of total microbial population as well as their community structure in activated sludge during 6:2 PAPs biotransformation were also investigated. 
PFAS
• 6:2/8:2 diPAP
     Literature Search
          Pubmed
          WOS
     Screening Results
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• 6:2 diPAP
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
• FtOH 6:2
     Screening Results
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• ^Per- and Polyfluoroalkyl Substances (PFAS)
     PFHpA (375-85-9)
          Literature Search
               Pubmed
               WOS
     PFPeA (2706-90-3)
          Literature Search
               Pubmed
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     FtOH 6:2 (647-42-7)
          Literature Search
               Pubmed
     6:2 diPAP (57677-95-9)
          Literature Search
               Pubmed
               WOS
     6:2/8:2 diPAP (943913-15-3)
          Literature Search
               Pubmed
               WOS
• PFHpA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
• PFPeA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic