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1338620 
Journal Article 
Review 
Bioreporters and biosensors for arsenic detection. Biotechnological solutions for a world-wide pollution problem 
Merulla, D; Buffi, N; Beggah, S; Truffer, F; Geiser, M; Renaud, P; van der Meer, JR 
In Press 
Yes 
Current Opinion in Biotechnology
ISSN: 0958-1669 
24 
3 
534-541 
English 
22999825 
WOS:000320829500023 
A wide variety of whole cell bioreporter and biosensor assays for arsenic detection has been developed over the past decade. The assays permit flexible detection instrumentation while maintaining excellent method of detection limits in the environmentally relevant range of 10-50μg arsenite per L and below. New emerging trends focus on genetic rewiring of reporter cells and/or integration into microdevices for more optimal detection. A number of case studies have shown realistic field applicability of bioreporter assays. 
IRIS
• Arsenic Hazard ID
     1. Initial Lit Search
          PubMed
          PubMed
          Considered New
          WOS
          Considered New
          ToxNet
          Considered New
          ToxNet
          Excluded
               Reviews
               Toxnet Duplicates
          ToxNet
          Excluded
               Reviews
               Toxnet Duplicates
          ToxNet
          Excluded
               Reviews
               Toxnet Duplicates
     2. Lit Search Updates through Oct 2015
          PubMed
          WOS
          ToxNet
          Initial Filter
               Reviews
          Considered
     4. Considered through Oct 2015
     6. Cluster Filter through Oct 2015
     7. Other Studies through Oct 2015
          Other
• Arsenic (Inorganic)
     1. Literature
          Lit search updates through Oct 2015
     2. Initial Filter
          Reviews
• Arsenic MOA
     1. MOA Literature Screening
          MOA Cluster
     3. Excluded
          Other not relevant
               Dragon Screened