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Citation
Tags
HERO ID
1464953
Reference Type
Journal Article
Title
A rapid and sensitive gas chromatography-mass spectrometry method for the quality control of perfumes: simultaneous determination of phthalates
Author(s)
Lopez-Nogueroles, M; Benede, JL; Chisvert, A; Salvador, A
Year
2013
Is Peer Reviewed?
Yes
Journal
Analytical Methods
ISSN:
1759-9660
EISSN:
1759-9679
Volume
5
Issue
2
Page Numbers
409-415
Language
English
DOI
10.1039/c2ay26130h
Web of Science Id
WOS:000312658600012
URL
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871777384&doi=10.1039%2fc2ay26130h&partnerID=40&md5=3f7101312620a5d2a04d419fb6f48280
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Abstract
A rapid and sensitive analytical gas chromatography-mass spectrometry (GC-MS) method for perfume analysis to determine the phthalates banned by the European Union Regulation on cosmetic samples is presented. This method has been tested in commercial alcoholic perfume samples for the determination of the following seven phthalates: dibutyl phthalate, bis(2-ethylhexyl) phthalate, bis(2-methoxyethyl) phthalate, n-pentyl-isopentylphthalate, di-n-pentyl phthalate, diisopentylphthalate and benzyl butyl phthalate. Sample evaporation and redissolution in ethanol is carried out before GC-MS analysis, with no dilution of the sample. External calibration and standard addition calibration are compared to detect possible matrix effects. External calibration could provide good results in some cases but standard addition calibration is recommended as matrix effects are observed in many cases in the determination of the target phthalates. The accuracy of the method has been proven by the analysis of quality control samples prepared from commercial free phthalate perfumes after spiking with known concentrations of the analytes. Accurate results were obtained with limits of detection in the ng mL(-1) range and good repeatability (relative standard deviations lower than 6%). The method was satisfactorily applied to the analysis of commercial perfume samples, and the results revealed considerable amounts of dibutyl phthalate and bis(2-ethylhexyl) phthalate in some of the analyzed samples.
Tags
IRIS
•
BBP (Butyl benzyl phthalate)
Literature Search
LitSearch Dec 2012
WOS
LitSearch Aug 2013-Apr 2014
Web of Science
Excluded: No Primary Data on Health Effects
Measurement methods
•
Phthalates – Targeted Search for Epidemiological Studies
Source – all searches
WOS
Excluded
Source – no date limit through June 2013 (Private)
WOS
Source - Dec 2013 Update (Private)
WOS
Source - Jun 2014 Update (Private)
WOS
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