The insect repellents: A silent environmental chemical toxicant to the health

Roy, DN; Goswami, R; Pal, A

HERO ID

3859187

Reference Type

Journal Article

Subtype

Review

Year

2017

Language

English

PMID

28171823

HERO ID 3859187
Material Type Review
In Press No
Year 2017
Title The insect repellents: A silent environmental chemical toxicant to the health
Authors Roy, DN; Goswami, R; Pal, A
Journal Environmental Toxicology and Pharmacology
Volume 50
Page Numbers 91-102
Abstract In recent years, a large number of insect repellents have been developed with the idea of consumer benefits. In addition to already known advantageous application of insect repellents, there is increasing concern about the potential toxicity in environment leading to health caused by random use of these compounds. An increasing number of evidence suggests that insect repellents may trigger undesirable hazardous interactions with biological systems with a potential to generate harmful effects including intermediate metabolites. Biotransformation followed by bioaccumulation (vice e versa) may be an important phenomenon for toxic response of this chemicals. In this review, we have summarized the current state of knowledge on the insect repellent toxicity, including biochemical pathway alteration under in vitro and in vivo conditions considering different classes of organisms, from lower to higher vertebrate. Furthermore, we have tried to incorporate the effects of insect repellent in light of some clinical reports. We hope this review would provide useful information on potential side effects of uncontrolled use of insect repellents.
Doi 10.1016/j.etap.2017.01.019
Pmid 28171823
Wosid WOS:000397833500011
Is Certified Translation No
Dupe Override No
Comments Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011672185&doi=10.1016%2fj.etap.2017.01.019&partnerID=40&md5=dbdf7737b5a7aa4074cb465fc07469e8
Is Public Yes
Language Text English
Keyword Insect repellents; Intermediate metabolites; Biotransformation; Bioaccumulation; Toxicity; Human health
Is Peer Review Yes