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3603324 
Journal Article 
Preliminary assessment on the bioaccessibility of contaminants of emerging concern in raw and cooked seafood 
Alves, RN; Maulvault, AL; Barbosa, VL; Cunha, S; Kwadijk, CJ; Álvarez-Muñoz, D; Rodríguez-Mozaz, S; Aznar-Alemany, Ò; Eljarrat, E; Barceló, D; Fernandez-Tejedor, M; Tediosi, A; Marques, A 
2017 
Yes 
Food and Chemical Toxicology
ISSN: 0278-6915
EISSN: 1873-6351 
104 
69-78 
English 
A preliminary assessment of the bioaccessibility of contaminants of emerging concern (CeCs), including perfluorinated compounds (PFCs; i.e. PFOS and PFUnA), brominated flame retardants (BFRs; i.e. BDE47, BDE100, α-HBCD) and pharmaceuticals and personal care products (PPCPs; i.e. venlafaxine, methylparaben and UV-filter OC) was performed in seafood species available in the European markets. Additionally, the effect of steaming on CeCs bioaccessibility was also investigated for the first time. Overall, steaming affected differentially contaminants' concentrations, for instance, decreasing PFOS levels in flounder, but increasing both BDE47 and BDE100. CeCs bioaccessibility varied according to seafood species and contaminant group, i.e. in general, lower bioaccessibility values were obtained for PBDEs (<70%, except for mackerel), while PFCs and PPCPs revealed higher bioaccessibility percentages (between 71 and 95%). The lowest bioaccessibility value was obtained for α-HBCD (mussel; 14%), whereas the highest percentage was observed in venlafaxine (mullet; 95%). Our preliminary study reports also, for the first time, the effects of steaming on CeCs bioaccessibility. In most cases, bioaccessibility was not affected by cooking, however, a decrease was observed in PBDEs and venlafaxine bioaccessibility in steamed mussels and mullet, respectively, thus lowering the potential health risks associated with seafood consumption. 
seafood; perfluorinated compounds; brominated flame retardants; pharmaceuticals and personal care products; bioaccessibility; steaming 
PFAS
• Additional PFAS (formerly XAgency)
• ^Per- and Polyfluoroalkyl Substances (PFAS)
     PFOA (335-67-1) and PFOS (1763-23-1)
          Literature Search – Adverse outcome pathway (2015-present)
               Pubmed
               WOS
     PFUnA (2058-94-8)
          Literature Search
               Pubmed
               WOS
• PFAS 150
     Literature Search Update December 2020
          PubMed
          WOS
     Literature Search August 2019
          PubMed
          Web of Science
     Screened Studies
          Supplemental
     Perfluorinated compounds
     Perfluorooctanesulfonic acid
     Perfluoroundecanoic acid
• PFAS Universe
     Data Source
          Web of Science
          Pubmed
     Perfluorooctanesulfonate
     Perfluorooctanesulfonic acid
     Perfluoroundecanoic acid
• PFNA
     Litsearch Update 2017-2018
          Toxline
     Literature Search
          Toxline
• PFUnA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
OW - HHRAB
• PFOA (335-67-1) and PFOS (1763-23-1)
     Literature Search – Adverse outcome pathway (2015-present)
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
     Literature Search Update (2013-2019)
          PubMed
          WOS