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3982038 
Journal Article 
Supplemental Data 
Effects of perfluorinated alkyl acids on cellular responses of MCF-10A mammary epithelial cells in monolayers and on acini formation in vitro: Supplementary materials 
Halsne, R; Tandberg, JI; Lobert, VH; Østby, GC; Thoen, E; Ropstad, E; Verhaegen, S 
2016 
Toxicology Letters
ISSN: 0378-4274
EISSN: 1879-3169 
259 
English 
is a supplement to 3749278 Effects of perfluorinated alkyl acids on cellular responses of MCF-10A mammary epithelial cells in monolayers and on acini formation in vitro
Supplementary materials 
PFAS
• ^Per- and Polyfluoroalkyl Substances (PFAS)
     PFOA (335-67-1) and PFOS (1763-23-1)
          Literature Search – Adverse outcome pathway (2015-present)
               Pubmed
               WOS
     PFUnA (2058-94-8)
          Literature Search
               Pubmed
               WOS
     PFDA (335-76-2)
          Literature Search
               Pubmed
               WOS
     PFNA (375-95-1)
          Literature Search
               Pubmed
               WOS
• PFDA
     Literature Search
          Pubmed
          WOS
     Screening Results
          In vitro/ex vivo/in silico
               Receptor activation
               Other mechanistic studies
     Title and Abstract Screening
          Full Text Screening
          Tagged as Supplemental
               Mechanistic or MOA
     Literature Searches (through April 2023 update and post-public comment/peer review)
          Title & Abstract Screening
               Full Text Screening
               Tagged as Supplemental
                    In vitro and in silico models
• PFNA
     Literature Search (August 2017)
          Pubmed
     Literature Search
          Pubmed
          WOS
     Screening Results
          In vitro/ex vivo/in silico
               Endocrine disruption
     Title and Abstract Screening
          Full Text Screening
               Excluded
                    Not relevant to PECO
• PFUnA
     Literature Search
          Pubmed
          WOS
     Screening Results
          In vitro/ex vivo/in silico
               Other mechanistic studies
OW - HHRAB
• PFOA (335-67-1) and PFOS (1763-23-1)
     Literature Search – Adverse outcome pathway (2015-present)
          Pubmed
          WOS