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Citation
Tags
HERO ID
681609
Reference Type
Journal Article
Subtype
Review
Title
Diethyl phthalate: A perspective
Author(s)
Kamrin, MA; Mayor, GH
Year
1991
Is Peer Reviewed?
Yes
Journal
Journal of Clinical Pharmacology
ISSN:
0091-2700
EISSN:
1552-4604
Volume
31
Issue
5
Page Numbers
484-489
Language
English
PMID
2050836
DOI
10.1002/j.1552-4604.1991.tb01908.x
Web of Science Id
WOS:A1991FM18300016
URL
https://search.proquest.com/docview/80619173?accountid=171501
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Abstract
A review of the toxicity and toxicokinetics of diethyl phthalate, a widely used solvent and fixative for cosmetic products and a plasticizer for packaging materials, is presented, including studies of human exposure, phthalate toxicity in experimental animals and in vitro studies, toxicokinetics and toxicology of diethyl phthalate, migration from packaging materials, and regulations regarding the use of diethyl phthalate. Studies of human workers exposed to high concentrations of phthalates show limited evidence of toxicity. Pharmacokinetic data suggest that the effects that are detected in animals at high doses are unlikely to occur at the much lower levels representative of human exposure.
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Diethyl phthalate (DEP)
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