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3350205 
Journal Article 
Dietary exposure to benzyl butyl phthalate in China 
Zhang, L; Jiang, DG; Sui, HX; Wu, PG; Liu, AD; Yang, DJ; Liu, ZP; Song, Y; Li, N 
2016 
Yes 
Biomedical and Environmental Sciences
ISSN: 0895-3988
EISSN: 2214-0190 
29 
5 
365-373 
English 
27353711 
WOS:000382905700007 
OBJECTIVE: Benzyl butyl phthalate (BBP) is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population.

METHODS: The BBP contents were detected in 7409 food samples from 25 food categories by gas chromatography-mass spectrometry operated in selected ion monitoring (SIM) mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake (TDI) of BBP established by European Food safety Agency.

RESULTS: It was found that BBP was undetectable in most samples and the highest level was 1.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged ⋝2 years was 1.03 μg/kg bw per day and the highest average exposure was found in 2-6 years old children (1.98 μg/kg bw per day). The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake (TDI) in worst scenario.

CONCLUSION: The health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern. 
Adolescent; Aged, 80 and over; Child, Preschool; Environmental Exposure; Environmental Pollutants/analysis; Food Contamination/analysis; Food Packaging; Gas Chromatography-Mass Spectrometry; Middle Aged; Phthalic Acids/analysis; Plasticizers/analysis; Young Adult; Benzyl butyl phthalate; Dietary exposure; Risk assessment; YPC4PJX59M 
IRIS
• BBP (Butyl benzyl phthalate)
     Literature Search
          Literature Search: January 2016 - June 2016
               Pubmed
          Literature Search: July 2016 - January 2017
               WOS
     Excluded: No Primary Data on Health Effects
          Exposure levels
• Dibutyl Phthalate (DBP)
     Database Searches
          Litsearch Jan 2016 - July 2016
               Pubmed
     Excluded: No Primary Data on Health Effects
          Not chemical specific
• Phthalates – Targeted Search for Epidemiological Studies
     Source – all searches
          Pubmed
          WOS
     Excluded
     Source - Dec 2016 Update (Private)
          Pubmed
          WOS