Health & Environmental Research Online (HERO)


Print Feedback Export to File
2914648 
Journal Article 
Concentrations of phthalates in bottled water under common storage conditions: Do they pose a health risk to children? 
Jeddi, MZ; Rastkari, N; Ahmadkhaniha, R; Yunesian, M 
2015 
Yes 
Food Research International
ISSN: 0963-9969
EISSN: 1873-7145 
ELSEVIER SCIENCE BV 
AMSTERDAM 
69 
256-265 
English 
Of recent concern is the migration of phthalates from plastic products such as Polyethylene Terephthalate (PET) bottles into the water contain. These concerns should be addressed, especially considering the steady growth of the consumption of bottled water and the toxicological effects of phthalates. In this regard, special attention should be paid to children's consumption because of their particular susceptibility to the effects of phthalates. The aim of this study was to determine the concentrations of phthalates, including dibutyl phthalate (DBP), butyl benzyl phthalate (BBP) and bis(2-ethylhexyl) phthalate (DEHP), in bottled water and to estimate the health risk of endocrine disrupting chemicals due to water intake in children for the first time.

Migration of phthalates was investigated in PET-bottled water under various storage conditions using gas chromatography-mass spectroscopy. A phthalate exposure assessment was performed to characterize their risk to the children's health via a calculated hazard quotient (HQ).

It seems that increase in the temperature and the duration of storage affect phthalate migration, but the level of DEHP in bottled water was always very low and does not exceed 26.83% of the U.S. EPA maximum concentration limit (MCL). In particular, phthalate migration was not substantial at low temperatures (<25 degrees C) and freezing conditions and the most abundant phthalate (DEHP) was not more than 10.6% MCL.

The estimated child intake ranged from 0.01 mu g/kg/day for BBP to 0.24 mu g/kg/day for DEHP. Estimated phthalate intakes are generally in the safe range and exposure decreased with increasing age. Toxicological risk assessment of the maximum concentrations measured revealed a maximum HQ of 0.012 in the worst condition. Furthermore, a negligible carcinogenic risk of 6.5 x 10(-7) for DEHP was observed. Consequently, risk evaluation showed that bottled water is safe for consumption by children. 
Phthalate; Preschooler; Endocrine disruptor chemical; Infant; Hazard quotient 
IRIS
• BBP (Butyl benzyl phthalate)
     Literature Search
          Litsearch March 2015 - June 2015
               WOS
     Excluded: No Primary Data on Health Effects
          Exposure levels
• Dibutyl Phthalate (DBP)
     Database Searches
          Litsearch March 2015 - June 2015
               WOS
          LitSearch Jul 2016 - Jan 2017
               Prior search overlap
               WoS
     Excluded: No Primary Data on Health Effects
          Exposure levels
          Fate and transport
     Litsearch June 2015 - Jan 2016
          Web of Science
• Phthalates – Targeted Search for Epidemiological Studies
     Source – all searches
          WOS
     Excluded
     Source – Dec 2015 Update (Private)
          WOS
     Source - Jun 2016 Update (Private)
          WOS