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HERO ID
2914648
Reference Type
Journal Article
Title
Concentrations of phthalates in bottled water under common storage conditions: Do they pose a health risk to children?
Author(s)
Jeddi, MZ; Rastkari, N; Ahmadkhaniha, R; Yunesian, M
Year
2015
Is Peer Reviewed?
Yes
Journal
Food Research International
ISSN:
0963-9969
EISSN:
1873-7145
Publisher
ELSEVIER SCIENCE BV
Location
AMSTERDAM
Volume
69
Page Numbers
256-265
Language
English
DOI
10.1016/j.foodres.2014.11.057
Web of Science Id
WOS:000352174000031
URL
https://search.proquest.com/docview/1673382702?accountid=171501http://www.sciencedirect.com/science/article/pii/S0963996914008114
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Abstract
Of recent concern is the migration of phthalates from plastic products such as Polyethylene Terephthalate (PET) bottles into the water contain. These concerns should be addressed, especially considering the steady growth of the consumption of bottled water and the toxicological effects of phthalates. In this regard, special attention should be paid to children's consumption because of their particular susceptibility to the effects of phthalates. The aim of this study was to determine the concentrations of phthalates, including dibutyl phthalate (DBP), butyl benzyl phthalate (BBP) and bis(2-ethylhexyl) phthalate (DEHP), in bottled water and to estimate the health risk of endocrine disrupting chemicals due to water intake in children for the first time.
Migration of phthalates was investigated in PET-bottled water under various storage conditions using gas chromatography-mass spectroscopy. A phthalate exposure assessment was performed to characterize their risk to the children's health via a calculated hazard quotient (HQ).
It seems that increase in the temperature and the duration of storage affect phthalate migration, but the level of DEHP in bottled water was always very low and does not exceed 26.83% of the U.S. EPA maximum concentration limit (MCL). In particular, phthalate migration was not substantial at low temperatures (<25 degrees C) and freezing conditions and the most abundant phthalate (DEHP) was not more than 10.6% MCL.
The estimated child intake ranged from 0.01 mu g/kg/day for BBP to 0.24 mu g/kg/day for DEHP. Estimated phthalate intakes are generally in the safe range and exposure decreased with increasing age. Toxicological risk assessment of the maximum concentrations measured revealed a maximum HQ of 0.012 in the worst condition. Furthermore, a negligible carcinogenic risk of 6.5 x 10(-7) for DEHP was observed. Consequently, risk evaluation showed that bottled water is safe for consumption by children.
Keywords
Phthalate; Preschooler; Endocrine disruptor chemical; Infant; Hazard quotient
Tags
IRIS
•
BBP (Butyl benzyl phthalate)
Literature Search
Litsearch March 2015 - June 2015
WOS
Excluded: No Primary Data on Health Effects
Exposure levels
•
Dibutyl Phthalate (DBP)
Database Searches
Litsearch March 2015 - June 2015
WOS
LitSearch Jul 2016 - Jan 2017
Prior search overlap
WoS
Excluded: No Primary Data on Health Effects
Exposure levels
Fate and transport
Litsearch June 2015 - Jan 2016
Web of Science
•
Phthalates – Targeted Search for Epidemiological Studies
Source – all searches
WOS
Excluded
Source – Dec 2015 Update (Private)
WOS
Source - Jun 2016 Update (Private)
WOS
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