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Citation
Tags
HERO ID
3864586
Reference Type
Journal Article
Title
Temporal Shifts in Poly- and Perfluoroalkyl Substances (PFASs) in North Atlantic Pilot Whales Indicate Large Contribution of Atmospheric Precursors
Author(s)
Dassuncao, C; Hu, XC; Zhang, X; Bossi, R; Dam, M; Mikkelsen, B; Sunderland, EM
Year
2017
Is Peer Reviewed?
1
Journal
Environmental Science & Technology
ISSN:
0013-936X
EISSN:
1520-5851
Volume
51
Issue
8
Page Numbers
4512-4521
Language
English
PMID
28350446
DOI
10.1021/acs.est.7b00293
Web of Science Id
WOS:000399859700041
Abstract
Poly- and perfluoroalkyl substances (PFASs) are persistent, bioaccumulative anthropogenic compounds associated with adverse health impacts on humans and wildlife. PFAS production changed in North America and Europe around the year 2000, but impacts on wildlife appear to vary across species and location. Unlike other mammal species, cetaceans lack the enzyme for transforming an important intermediate precursor (perfluorooctane sulfonamide: FOSA), into a prevalent compound in most wildlife (perfluorooctanesulfonate: PFOS). Thus, their tissue burden differentiates these two compounds while other mammals contain PFOS from both direct exposure and precursor degradation. Here we report temporal trends in 15 PFASs measured in muscle from juvenile male North Atlantic pilot whales (Globicephala melas) harvested between 1986 and 2013. FOSA accounted for a peak of 84% of the 15 PFASs around 2000 but declined to 34% in recent years. PFOS and long-chained PFCAs (C9-C13) increased significantly over the whole period (2.8% yr(-1) to 8.3% yr(-1)), but FOSA declined by 13% yr(-1) after 2006. Results from FOSA partitioning and bioaccumulation modeling forced by changes in atmospheric inputs reasonably capture magnitudes and temporal patterns in FOSA concentrations measured in pilot whales. Rapid changes in atmospheric FOSA in polar and subpolar regions around 2000 helps to explain large declines in PFOS exposure for species that metabolize FOSA, including seafood consuming human populations. This work reinforces the importance of accounting for biological exposures to PFAS precursors.
Tags
PFAS
•
Additional PFAS (formerly XAgency)
•
Expanded PFAS SEM (formerly PFAS 430)
Litsearch: September 2019
PubMed
Web of Science
Not prioritized for screening
Perfluorooctane
•
^Per- and Polyfluoroalkyl Substances (PFAS)
PFOA (335-67-1) and PFOS (1763-23-1)
Literature Search – Adverse outcome pathway (2015-present)
Pubmed
WOS
PFOSA (754-91-6)
Literature Search
WOS
•
PFAS 150
Literature Search Update December 2020
PubMed
WOS
Literature Search August 2019
PubMed
Web of Science
Perfluorinated compounds
Perfluorooctane
Perfluorooctanesulfonate
Perfluorooctanesulfonic acid
•
PFNA
Litsearch Update 2017-2018
PFAS Untag
Literature Search
Toxline
PFNA May 2019 Update
Toxnet
Title and Abstract Screening
Excluded
Not relevant to PECO
•
PFOA (335-67-1) and PFOS (1763-23-1)
Literature Search – Adverse outcome pathway (2015-present)
Pubmed
WOS
Screening Results
Excluded/Not on Topic
Literature Search Update (2013-2019)
PubMed
WOS
•
PFOSA
Literature Search
Pubmed
WOS
Screening Results
Excluded/Not on Topic
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