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1256375 
Journal Article 
Determination of per- and polyfluorinated substances in airborne particulate matter by microwave-assisted extraction and liquid chromatography-tandem mass spectrometry 
Beser, MI; Pardo, O; Beltrán, J; Yusà, V 
2011 
Yes 
Journal of Chromatography A
ISSN: 0021-9673
EISSN: 1873-3778 
1218 
30 
4847-4855 
English 
is supplemented by 11350179 Determination of per- and polyfluorinated substances in airborne: Supplementary content
A sensitive and confirmatory analytical method has been developed for the determination of 12 ionic per- and polyfluorinated alkyl substances (PFAS) in fine airborne particulate matter (PM2.5) at trace levels. The proposed method includes extraction of PM2.5-bound PFAS by microwave-assisted extraction (MAE) followed by centrifugation and injection into the liquid chromatograph coupled to a triple quadrupole tandem mass spectrometry system (LC-MS/MS). The main parameters affecting the performance of MAE were optimised using statistical design of experiments (DoE). Recoveries ranged from 83 to 120% and the method quantification limit (MQL) was 1.4 pg m(-3), when air volumes of 720 m(3) were sampled. This method was successfully applied to 41 samples collected from five stations of the monitoring network of the Valencian Regional Government (Spain) during April-July 2010. Eight out of 12 PFCs investigated were quantified in at least one sample (PFBA, PFPeA, PFHxS, 6:2 FTS, PFOA, PFNA, PFOS and PFDA). The measured concentrations ranged from 1.4 to 34.3 pg m(-3). 
PFCs; PFAS; PM2.5; MAE; LC-MS/MS; Experimental design 
• PM Provisional Assessment (2012 Project Page)
     Experimental Studies
          PM Components and Sources
PFAS
• Additional PFAS (formerly XAgency)
• Expanded PFAS SEM (formerly PFAS 430)
     Litsearch: September 2019
          Web of Science
     Not prioritized for screening
     6:2 Fluorotelomer sulfonic acid
• ^Per- and Polyfluoroalkyl Substances (PFAS)
     PFDA (335-76-2)
          Literature Search
               Pubmed
               WOS
     PFNA (375-95-1)
          Literature Search
               Pubmed
               WOS
     PFPeA (2706-90-3)
          Literature Search
               Pubmed
               WOS
     PFBA (375-22-4)
          Literature Search
               Pubmed
               WOS
     PFHxS (355-46-4)
          Literature search
               Pubmed
               WOS
     FtS 6:2 (27619-97-2)
          Literature Search
               Pubmed
               WOS
• PFAS 150
     Literature Search Update December 2020
          PubMed
     Literature Search August 2019
          PubMed
     Not prioritized for screening
     Perfluorobutanoic acid
     Perfluorodecanoic acid
     Perfluorohexanesulfonic acid
     Perfluorononanoic acid
     Perfluorooctanesulfonic acid
     Perfluoropentanoic acid
• PFAS Universe
     Data Source
          Web of Science
          Pubmed
     6:2 Fluorotelomer sulfonic acid
     Perfluorobutanoate
     Perfluorobutanoic acid
     Perfluorodecanoate
     Perfluorodecanoic acid
     Perfluorohexanesulfonate
     Perfluorohexanesulfonic acid
     Perfluorooctanesulfonate
     Perfluorooctanesulfonic acid
     Perfluorooctanoate
     Perfluoropentanoate
     Perfluoropentanoic acid
     Sodium perfluorohexanesulfonate
     Perfluorooctanoic acid
• PFBA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
     Protocol References
     Scopus: April 2021
• PFDA
     Literature Search
          Pubmed
          WOS
     Scopus: April 2021
     Screening Results
          Excluded/Not on Topic
     Title and Abstract Screening
          Excluded
     Literature Searches (through April 2023 update and post-public comment/peer review)
          Title & Abstract Screening
               Excluded
• PFHxA
     Scopus: April 2021
     HAWC
• PFHxS
     Database searches
          Pubmed
          Toxline
          WOS
          Scopus
     Excluded
          TiAb
• PFNA
     Literature Search (August 2017)
          Pubmed
     PFNA Literature Search pre-2019
          Pubmed
          WOS
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
     Title and Abstract Screening
          Excluded
               Not relevant to PECO
• PFPeA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic