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1256375 
Journal Article 
Determination of per- and polyfluorinated substances in airborne particulate matter by microwave-assisted extraction and liquid chromatography-tandem mass spectrometry 
Beser, MI; Pardo, O; Beltrán, J; Yusà, V 
2011 
Yes 
Journal of Chromatography A
ISSN: 0021-9673
EISSN: 1873-3778 
1218 
30 
4847-4855 
English 
A sensitive and confirmatory analytical method has been developed for the determination of 12 ionic per- and polyfluorinated alkyl substances (PFAS) in fine airborne particulate matter (PM2.5) at trace levels. The proposed method includes extraction of PM2.5-bound PFAS by microwave-assisted extraction (MAE) followed by centrifugation and injection into the liquid chromatograph coupled to a triple quadrupole tandem mass spectrometry system (LC-MS/MS). The main parameters affecting the performance of MAE were optimised using statistical design of experiments (DoE). Recoveries ranged from 83 to 120% and the method quantification limit (MQL) was 1.4 pg m(-3), when air volumes of 720 m(3) were sampled. This method was successfully applied to 41 samples collected from five stations of the monitoring network of the Valencian Regional Government (Spain) during April-July 2010. Eight out of 12 PFCs investigated were quantified in at least one sample (PFBA, PFPeA, PFHxS, 6:2 FTS, PFOA, PFNA, PFOS and PFDA). The measured concentrations ranged from 1.4 to 34.3 pg m(-3). 
PFCs; PFAS; PM2.5; MAE; LC-MS/MS; Experimental design 
• PM Provisional Assessment (2012 Project Page)
     Experimental Studies
          PM Components and Sources
PFAS
• FtS 6:2
     Literature Search
          Pubmed
          WOS
• ^Per- and Polyfluoroalkyl Substances (PFAS)
     PFDA (335-76-2)
          Literature Search
               Pubmed
               WOS
     PFNA (375-95-1)
          Literature Search
               Pubmed
               WOS
     PFPeA (2706-90-3)
          Literature Search
               Pubmed
               WOS
     PFBA (375-22-4)
          Literature Search
               Pubmed
               WOS
     PFHxS (355-46-4)
          Literature search
               Pubmed
               WOS
     FtS 6:2 (27619-97-2)
          Literature Search
               Pubmed
               WOS
• PFBA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
• PFDA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
     Title and Abstract Screening
          Excluded
• PFHxS
     Literature Search
          PubMed
          WOS
     Screening Results
          Excluded/Not on Topic
• PFNA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
     PFNA Literature Search pre-2019
          WOS
          Pubmed
• PFPeA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic