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3229677 
Journal Article 
Impact of clothing on dermal exposure to phthalates: Observations and insights from sampling both skin and clothing 
Gong, M; Weschler, CJ; Zhang, Y 
2016 
Yes 
Environmental Science and Technology
ISSN: 0013-936X
EISSN: 1520-5851 
50 
4350-4357 
English 
is supplemented by 3479728 Supporting information:
Clothing can either retard or accelerate dermal exposure to phthalates. To investigate the impact of clothing on dermal exposure to six phthalates (DMP/DEP/DiBP/DnBP/BBzP/DEHP) in real environments, two sets of experiments have been conducted: (1) Skin wipes were collected from 11 adults to examine the phthalate levels on both bare-skin (hand/forehead) and clothing-covered body locations (arm/back/calf); (2) Five adults were asked to wear just-washed jeans for 1 day (1(st) experiment), 5 days (2(nd) experiment), and 10 days (3(rd) experiment). Phthalate levels on their legs were measured on selected days during the wearing period, and phthalate levels in the jeans were measured at the end of each experiment and again after washing. Measured phthalate levels on body locations covered by clothing were lower than those on uncovered locations, but still substantial. Dermal uptake would be underestimated by a factor of 2 to 5 if absorption through body locations covered by clothing were neglected. Phthalate levels in the jeans and on the legs increased with the wearing time. However, the levels in the jeans and on the legs were not strongly correlated, indicating that other pathways, e.g, contact with bedding or bedclothes, likely contribute to the levels on the legs. The efficiency with which laundering washing removed phthalates from the jeans increased with decreasing Kow; median values ranged from very low (<5%) for DEHP to very high (∼75%) for DMP. 
IRIS
• Dibutyl Phthalate (DBP)
     Database Searches
          Litsearch Jan 2016 - July 2016
               Pubmed
     Excluded: No Primary Data on Health Effects
          Exposure levels
• Diethyl phthalate (DEP)
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          Jun 2016 update
               Pubmed
               Web of Science
          Jan 2017 update
               Prior search overlap
               Web of Science
          Jan 2020 update
               PubMed
               Web of Science
     Excluded: No Primary Data on Health Effects
          Exposure levels
• Diisobutyl Phthalate (DIBP) Final
     Database Searches
          June 2016 Update
               New for this search
               Pubmed
          January 2017 Update
               Web of Science
     No Primary Data on Toxic Effects
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• Phthalates – Targeted Search for Epidemiological Studies
     Source – all searches
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          WOS
     Excluded
     Source - Jun 2016 Update (Private)
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     Source - Dec 2016 Update (Private)
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