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3858500 
Journal Article 
Perfluoroalkyl acids (PFAAs) in the Pra and Kakum River basins and associated tap water in Ghana 
Essumang, DK; Eshun, A; Hogarh, JN; Bentum, JK; Adjei, JK; Negishi, J; Nakamichi, S; Habibullah-Al-Mamun, M; Masunaga, S 
2017 
Yes 
Science of the Total Environment
ISSN: 0048-9697
EISSN: 1879-1026 
579 
729-735 
English 
Perfluoroalkyl acids (PFAAs) are persistent environmental pollutants that have been detected in various media including human serum. Due to concerns regarding their bioaccumulation and possible negative health effects, an understanding of routes of human exposure is necessary. PFAAs are recalcitrant in many water treatment processes, making drinking water a potential source of human exposure. This study presents the first report on contamination from PFAAs in river and drinking water in Ghana. The targeted PFAAs were perfluoroalkyl carboxylic acids (PFCAs) with C4-14 carbon chain and perfluoroalkane sulphonic acids (PFSAs) with C6, 8, 10. Five PFAA congeners - PFOA, PFOS, PFHxA, PFDA and PFPeA - were commonly detected in river and tap water. The mean concentrations of ∑PFAAs in the Kakum and Pra Rivers were 281 and 398ng/L, while tap water (supplied from the treatment of water from those rivers) contained concentrations of 197 and 200ng/L, respectively. PFOA and PFOS constituted about 99% of the ∑PFAAs. The risk quotient (RQ) attributed to drinking of tap water was estimated at 1.01 and 1.74 for PFOA and PFOS, respectively. For a country that has not produced these compounds, the RQs were unexpectedly high, raising concerns particularly about contamination from such emerging pollutants in local water sources. The study revealed limitations of local tap water treatment in getting rid of these emerging pollutants. 
Perfluorinated compounds; Pra River; Kakum River; Perfluorooctanoic acid; Perfluorooctane sulphonate 
• ^Per- and Polyfluoroalkyl Substances (PFAS)
     PFOA (335-67-1) and PFOS (1763-23-1)
          Literature Search – Adverse outcome pathway (2015-present)
               Pubmed
               WOS
     PFDA (335-76-2)
          Literature Search
               Pubmed
               WOS
     PFHxA (307-24-4)
          Literature Search
               Pubmed
               WOS
     PFPeA (2706-90-3)
          Literature Search
               Pubmed
               WOS
• PFDA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
     Title and Abstract Screening
          Excluded
• PFNA
     Literature Search
          Toxline
     PFNA May 2019 Update
          Toxnet
• PFOA (335-67-1) and PFOS (1763-23-1)
     Literature Search – Adverse outcome pathway (2015-present)
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
     Literature Search Update (2013-2019)
          PubMed
          WOS
• PFPeA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic