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HERO ID
2915548
Reference Type
Journal Article
Title
Exposure to select phthalates and phenols through use of personal care products among Californian adults and their children
Author(s)
Philippat, C; Bennett, D; Calafat, AM; Picciotto, IH
Year
2015
Is Peer Reviewed?
Yes
Journal
Environmental Research
ISSN:
0013-9351
EISSN:
1096-0953
Publisher
Academic Press Inc.
Location
SAN DIEGO
Book Title
Environ Res. 2015, Jul; 140:369-76. [Environmental research]
Volume
140
Page Numbers
369-376
Language
English
PMID
25929801
DOI
10.1016/j.envres.2015.04.009
Web of Science Id
WOS:000357904100041
URL
https://search.proquest.com/docview/2000273750?accountid=171501
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Abstract
INTRODUCTION:
Certain phenols and phthalates are used in many consumer products including personal care products (PCPs).
AIMS:
We aimed to study the associations between the use of PCPs and urinary concentrations of biomarkers of select phenols and phthalates among Californian adults and their children. As an additional aim we compared phenols and phthalate metabolites concentrations measured in adults and children urine samples collected the same day.
METHODS:
Our study relied on a subsample of 90 adult-child pairs participating in the Study of Use of Products and Exposure Related Behavior (SUPERB). Each adult and child provided one to two urine samples in which we measured concentrations of selected phenols and phthalate metabolites. We computed Spearman correlation coefficients to compare concentrations measured in adults and children urine samples collected the same day. We used adjusted linear and Tobit regression models to study the associations between the use of PCPs in the past 24h and biomarker concentrations.
RESULTS:
Benzophenone-3 and parabens concentrations were higher in adults compared to their children. Conversely children had higher mono-n-butyl phthalate and mono-isobutyl phthalate concentrations. No significant difference was observed for the other compounds. The total number of different PCPs used was positively associated with urinary concentrations of methyl, propyl and butyl parabens and the main metabolite of diethyl phthalate in adults. Among children, the use of a few specific products including liquid soap, hair care products and sunscreen was positively associated with urinary concentrations of some phenols or phthalate metabolites.
DISCUSSION:
These results strengthen the body of evidence suggesting that use of PCPs is an important source of exposure to parabens and diethyl phthalate in adults and provide data on exposure to selected phenols and phthalates through use of PCPs in children.
Keywords
Endocrine disruptors; Parabens; Personal care products; Phenols; Phthalates; Temporal variability
Tags
IRIS
•
Dibutyl Phthalate (DBP)
Database Searches
Litsearch March 2015 - June 2015
Pubmed
LitSearch Jul 2016 - Jan 2017
Prior search overlap
PubMed
WoS
Excluded: No Primary Data on Health Effects
Exposure levels
Litsearch June 2015 - Jan 2016
Web of Science
•
Diethyl phthalate (DEP)
Database searches
Jun 2015 update
Pubmed
Jan 2020 update
PubMed
Web of Science
Excluded: No Primary Data on Health Effects
Exposure levels
•
Diisobutyl Phthalate (DIBP) Final
Database Searches
December 2015 Update
New for This Search
Pubmed
Web of Science
June 2016 Update
Pubmed
Toxline
Web of Science
January 2017 Update
July 2017 Update
No Primary Data on Toxic Effects
Exposure levels
•
Phthalates – Targeted Search for Epidemiological Studies
Source – all searches
Pubmed
WOS
Excluded
Source – Dec 2015 Update (Private)
Pubmed
WOS
Source - Jun 2016 Update (Private)
WOS
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