US EPA

IRIS
• Ammonia
     Literature Search Update – March 2013 (private)
     Literature Search Results
     Cited 2016
          Supplemental
• tert-Amyl ethyl ether (TAEE)
     Initial Litsearch 6/2018
     From PPRTV
• Arsenic Hazard ID
• Arsenic (Inorganic)
     Cited in Volume 1
• Benzo(a)pyrene (BaP)
     Considered
     Cited
          Guidance
• Biphenyl
     Cited References
• tert-Butanol
     Cited in Document
• n-Butanol
     • Cited 2016 Public Comment Draft
          Tox Review
          Supplementary Materials
• tert-Butanol
     Cited in Public Comment Draft – May 2016
          Toxicological Review
• Chloroform Combined (current)
     Chloroform (original)
     Chloroform (current)
• Chromium VI
     Not in Lit Search
• Cobalt
     Cobalt IAP/Protocol
          Exclude
• 1,4-Dioxane - with inhalation update
     Final (2013)
     External Review Draft (2011)
• ETBE
     Cited in Document
• Ethylbenzene
     Protocol template references
• Formaldehyde
     Nervous system effects
          Cited
          Guidance or background material cited in this section
     Retroactive RIS import
          2013
               HCHON tox Cited Ref 022713
• Hexabromocyclododecane (HBCD)
• Inorganic Mercury Salts (2)
     Litcite References – Protocol
• Libby Amphibole Asbestos (Draft, 2011)
• Methanol (Non-Cancer)
     Cited in Final (2013)
     Cited in External Review Draft (2013)
     Ramazzini
• Methylmercury
     Cited in Document
     Protocol Assessment
• Naphthalene
• Nitrate/Nitrite
     Other resources cited in assessment
• PCBs
     Cited (Nov 2012)
     IRIS assessment protocol template
• RDX (121-82-4)
     Cited 2015 (private)
• Trimethylbenzenes (Interagency Science Discussion Draft)
     Primary Literature Search
     Primary Literature Search- Considered
          Cited
     Cited August 2016
          Cited Toxicological Review
          Cited Supplemental Information
• Trimethylbenzenes (TMB)
     Considered Studies
          Other
     Cited Studies
          Guidance
          EPA
     Cited in Tox Review – Revised TMBs Draft
     Cited in Supplemental Information – Revised TMBs Draft
     Cited in Revised TMBs Draft - All
• Uranium Toxicological Review
     Literature cited in ATSDR 2013 Toxicological Profile for Uranium
     Additional Strategies
• Vanadium Compounds - Problem Formulation
     Manual review of existing IRIS and PPRTV assessments
          IRIS 2011/2014
     Combined data set
          Dataset for title/abstract screening
               Excluded- PECO criteria not met (TIAB)
• Vanadium Inhalation
     Combined Dataset
          Dataset for title/abstract screening
               Excluded- PECO criteria not met (TIAB)
     Cited in Protocol
• Vanadium Pentoxide (Draft, 2011)
IRIS Legacy
• Naphthalene – Acute (2022)
OPPT REs
• OPPT_1,4-Dioxane_C. Engineering
     Data screening total
          Screening: Excluded
• OPPT_1,4-Dioxane_D. Exposure
     Total – title/abstract screening
          Off topic
• OPPT_1,4-Dioxane_E. Fate
     Total – title/abstract screening
          Off topic
• OPPT_1,4-Dioxane_F. Human Health
     Total – title/abstract screening
          Off topic
• OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_F. Human Health
     Total – title/abstract screening
          On topic
               Peer review
                    Secondary source/ Review
               Cited in IRIS document or IRIS HERO page
• OPPT_Methylene Chloride_A. Summary
     Cited in TSCA RE related document
• PFBA
     Protocol References
     Supplemental References
• PFBS
     Included
          Supporting References
• PFDA
• PFHxA
     Title and Abstract Screening
          Tagged as Supplemental
               Background/Exposure References
     HAWC
• PFHxS
• PFNA
• PFOA and PFOS OW MCLG Approaches
     Cited in White Papers
• Naphthalene (2021 Evidence mapping publication)
• Project 9 – Soil and Dust Ingestion
     Cited October 2016
          Carcinogenicity Assessment- Cited
          Supplemental Information - Cited
• Ramazzini Institute