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Citation
Tags
HERO ID
1239433
Reference Type
Technical Report
Subtype
EPA Report
Title
Benchmark dose technical guidance
Author(s)
U.S. Environmental Protection Agency :: U.S. EPA
Year
2012
Is Peer Reviewed?
Yes
Publisher
U.S. Environmental Protection Agency, Risk Assessment Forum
Location
Washington, DC
Report Number
EPA100R12001
Number of Pages
99
Language
English
URL
https://www.epa.gov/risk/benchmark-dose-technical-guidance
Tags
IRIS
•
Ammonia
Literature Search Update – March 2013 (private)
Literature Search Results
Cited 2016
Supplemental
•
tert-Amyl ethyl ether (TAEE)
Initial Litsearch 6/2018
From PPRTV
•
Arsenic (Inorganic)
Cited in Volume 1
•
Benzo(a)pyrene (BaP)
Considered
Cited
Guidance
•
Biphenyl
Cited References
•
tert-Butanol
Cited in Document
•
n-Butanol
• Cited 2016 Public Comment Draft
Tox Review
Supplementary Materials
•
tert-Butanol
Cited in Public Comment Draft – May 2016
Toxicological Review
•
Chloroform Combined (current)
Chloroform (original)
Chloroform (current)
•
Chromium VI
Not in Lit Search
•
Cobalt
Cobalt IAP/Protocol
Exclude
•
1,4-Dioxane - with inhalation update
Final (2013)
External Review Draft (2011)
•
ETBE
Cited in Document
•
Ethylbenzene
Protocol template references
•
Formaldehyde [archived]
Nervous system effects
Cited
Guidance or background material cited in this section
Retroactive RIS import
2013
HCHON tox Cited Ref 022713
•
Hexabromocyclododecane (HBCD)
•
Inorganic Arsenic (7440-38-2) [Final 2025]
•
Inorganic Mercury Salts (2)
Litcite References – Protocol
•
Libby Amphibole Asbestos (Draft, 2011)
•
Methanol (Non-Cancer)
Cited in Final (2013)
Cited in External Review Draft (2013)
Ramazzini
•
Methylmercury
Cited in Document
Protocol Assessment
•
Naphthalene
•
Nitrate/Nitrite
Assessment resources and general references
•
PCBs
Cited (Nov 2012)
IRIS assessment protocol template
•
RDX (121-82-4)
Cited 2015 (private)
•
Trimethylbenzenes (Interagency Science Discussion Draft)
Primary Literature Search
Primary Literature Search- Considered
Cited
Cited August 2016
Cited Toxicological Review
Cited Supplemental Information
•
Trimethylbenzenes (TMB)
Considered Studies
Other
Cited Studies
Guidance
EPA
Cited in Tox Review – Revised TMBs Draft
Cited in Supplemental Information – Revised TMBs Draft
Cited in Revised TMBs Draft - All
•
Uranium Toxicological Review
Additional Strategies
Literature cited in ATSDR 2013 Toxicological Profile for Uranium
•
Vanadium Compounds - Problem Formulation
Manual review of existing IRIS and PPRTV assessments
IRIS 2011/2014
Combined data set
Dataset for title/abstract screening
Excluded- PECO criteria not met (TIAB)
•
Vanadium Inhalation
Combined Dataset
Dataset for title/abstract screening
Excluded- PECO criteria not met (TIAB)
Cited in Protocol
•
Vanadium Pentoxide (Draft, 2011)
IRIS Legacy
•
Naphthalene – Acute (2022)
OPPT REs
•
OPPT_1,4-Dioxane_C. Engineering
Data screening total
Screening: Excluded
•
OPPT_1,4-Dioxane_D. Exposure
Total – title/abstract screening
Off topic
•
OPPT_1,4-Dioxane_E. Fate
Total – title/abstract screening
Off topic
•
OPPT_1,4-Dioxane_F. Human Health
Total – title/abstract screening
Off topic
•
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_F. Human Health
Total – title/abstract screening
On topic
Peer review
Secondary source/ Review
Cited in IRIS document or IRIS HERO page
•
OPPT_Methylene Chloride_A. Summary
Cited in TSCA RE related document
PFAS
•
6:2 Fluorotelomer sulfonic acid
6:2 Fluorotelomer sulfonic acid
•
PFBA
Protocol References
Supplemental References
•
PFBS
Included
Supporting References
•
PFDA
•
PFHxA
Title and Abstract Screening
Tagged as Supplemental
Background/Exposure References
HAWC
•
PFHxS
•
PFNA
•
PFOA and PFOS OW MCLG Approaches
Cited in White Papers
•
Naphthalene (2021 Evidence mapping publication)
•
Project 9 – Soil and Dust Ingestion
Cited October 2016
Carcinogenicity Assessment- Cited
Supplemental Information - Cited
•
Ramazzini Institute
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