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Technical Report 
EPA Report 
Guidelines for carcinogen risk assessment 
U.S. Environmental Protection Agency :: U.S. EPA 
U.S. Environmental Protection Agency, Risk Assessment Forum 
Washington, DC 
is supplemented by 088823 Supplemental guidance for assessing susceptibility from early-life exposure to carcinogens
The Guidelines for Carcinogen Risk Assessment provide EPA staff with guidance for developing and using risk assessments. They also provide basic information to the public about the Agency's risk assessment methods. 
Risk; Risk Assessment 
• Ammonia
     Literature Search – March 2012 (private)
     Literature Search Results
     Not Chemical Specific
          Guidance, notices
     Cited 2016
• Arsenic Hazard ID
• Arsenic (Inorganic)
     Cited in Volume 1
• Benzo(a)pyrene (BaP)
• Biphenyl
     Cited References
          Other studies
               Dose-response assessment
• tert-Butanol
     Cited in Document
• n-Butanol
     • Cited 2016 Public Comment Draft
          Tox Review
• tert-Butanol
     Cited in Public Comment Draft – May 2016
          Toxicological Review
          Supplemental Materials
• Chloroprene
     Cited 2009 Draft
     Cited 2010 Final
• Chromium VI
     Not in Lit Search
• DCM (Dichloromethane) (Final, 2011)
• 1,4-Dioxane - with inhalation update
     Final (2013)
     External Review Draft (2011)
     Cited in Document
     Not in Lit Search
• Ethylbenzene
• Hexabromocyclododecane (HBCD)
• Libby Amphibole Asbestos (Draft, 2011)
• Methanol (Non-Cancer)
     Cited in Final (2013)
     Cited in External Review Draft (2013)
• Naphthalene
• RDX (121-82-4)
     Cited 2015 (private)
• Tetrachloroethylene (Perc) (Final, 2012)
• Trichloroacetic acid (TCA) (Final, 2011)
• Trichloroethylene (TCE) (Final, 2011)
     All References
     Cancer Epi
     Liver Issues
• Trimethylbenzenes (Interagency Science Discussion Draft)
     Primary Literature Search
     Primary Literature Search- Considered
     Cited August 2016
          Cited Toxicological Review
          Cited Supplemental Information
• Trimethylbenzenes (TMB)
     Considered Studies
     Cited Studies
     Cited in Tox Review – Revised TMBs Draft
     Cited in Revised TMBs Draft - All
• Vanadium Pentoxide (Draft, 2011)
• ISA-Lead (2013 Final Project Page)
          2nd Draft
          3rd Draft
          1st Draft
          2nd Draft
          Final Cited
• ISA-Ozone (2013 Final Project Page)
          1st Draft
          2nd Draft
          3rd Draft
     Health Effects
• ISA-PM (2009 Final Project Page)
     2009 Final
• ISA-PM (current)
     1st Draft
     Final ISA
     Cited in First ERD Nov2015
     Cited Second ERD Dec2016
     Cited in Final ISA Dec2017
          Chapter 5 – Health
     Supplemental References
          Supporting References
• Exposure Factors Handbook (Post 2011)
     Chapter 1
• Mouse Lung Tumor
• Nanoscale Carbon
     All References Cited
     External Review Draft
     Peer Reviewed Draft
               Lower Priority Areas: Appendices G and H
     Final Case Study
          Product Life Cycle
               Lower Priority Areas: Appendices G and H
          Transport & Fate
               Lower Priority Areas: Appendices G and H
          Exposure, Uptake, and Dose
               Lower Priority Areas: Appendices G and H
               Lower Priority Areas: Appendices G and H
• Nanoscale Silver
     External Review Draft
     Final Case Study
          Exposure, Uptake and Dose
• Ramazzini Institute