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86237 
Technical Report 
EPA Report 
Guidelines for carcinogen risk assessment 
U.S. Environmental Protection Agency :: U.S. EPA 
2005 
Yes 
U.S. Environmental Protection Agency, Risk Assessment Forum 
Washington, DC 
EPA/630/P-03/001F 
1-166 
166 
English 
is supplemented by 088823 Supplemental guidance for assessing susceptibility from early-life exposure to carcinogens
The Guidelines for Carcinogen Risk Assessment provide EPA staff with guidance for developing and using risk assessments. They also provide basic information to the public about the Agency's risk assessment methods. 
Risk; Risk Assessment 
PB2005-105899 
• Ammonia
     Literature Search – March 2012 (private)
     Literature Search Results
     Not Chemical Specific
          Guidance, notices
     Cited 2016
          ToxReview
• Arsenic Hazard ID
• Arsenic (Inorganic)
     Cited in Volume 1
• Benzo(a)pyrene (BaP)
     Considered
     Cited
          Guidance
          Carcinogenicity
• Biphenyl
     Considered
     Cited References
          Other studies
               Dose-response assessment
          Guidance
• tert-Butanol
     Cited in Document
• n-Butanol
     • Cited 2016 Public Comment Draft
          Tox Review
• tert-Butanol
     Cited in Public Comment Draft – May 2016
          Toxicological Review
          Supplemental Materials
• Chloroprene
     Cited 2009 Draft
     Cited 2010 Final
• Chromium VI
     Not in Lit Search
• DCM (Dichloromethane) (Final, 2011)
• 1,4-Dioxane - with inhalation update
     Final (2013)
     External Review Draft (2011)
• ETBE
     Cited in Document
     Not in Lit Search
• Ethylbenzene
• Hexabromocyclododecane (HBCD)
• Libby Amphibole Asbestos (Draft, 2011)
• Methanol (Non-Cancer)
     Cited in Final (2013)
     Cited in External Review Draft (2013)
     Ramazzini
• Naphthalene
• RDX (121-82-4)
     Cited 2015 (private)
• Tetrachloroethylene (Perc) (Final, 2012)
     Hazard
          Genotox
• Trichloroacetic acid (TCA) (Final, 2011)
• Trichloroethylene (TCE) (Final, 2011)
     All References
     Hazard
     Cancer Epi
     Genotox
     Kidney
     Liver
     Respiratory
     Dose-Response
     Non-Cancer
     Cancer
     Liver Issues
• Trimethylbenzenes (Interagency Science Discussion Draft)
     Primary Literature Search
     Primary Literature Search- Considered
          Cited
     Cited August 2016
          Cited Toxicological Review
          Cited Supplemental Information
• Trimethylbenzenes (TMB)
     Considered Studies
          Other
     Cited Studies
          Guidance
          EPA
     Cited in Tox Review – Revised TMBs Draft
     Cited in Revised TMBs Draft - All
• Vanadium Pentoxide (Draft, 2011)
NAAQS
• ISA-Lead (2013 Final Project Page)
     Cited
          2nd Draft
          3rd Draft
          Final
• ISA-NOx
     Cited
          1st Draft
          2nd Draft
          Final
          Final Cited
• ISA-Ozone (2013 Final Project Page)
     Considered
     Cited
          1st Draft
          2nd Draft
          3rd Draft
          Final
     Health Effects
• ISA-PM (2009 Final Project Page)
     2009 Final
• ISA-PM (current)
     1st Draft
          P-ES-A
     Final ISA
          P-ES-A
• ISA-SOx
     Considered
     Cited in First ERD Nov2015
     Cited Second ERD Dec2016
     Cited in Final ISA Dec2017
          Chapter 5 – Health
PFAS
• PFBA
     Supplemental References
• PFBS
     Included
          Supporting References
• Exposure Factors Handbook (Post 2011)
     Chapter 1
     Glossary
• Mouse Lung Tumor
• Nanoscale Carbon
     All References Cited
     External Review Draft
          Impacts
     Peer Reviewed Draft
          Impacts
               Lower Priority Areas: Appendices G and H
     Final Case Study
          Product Life Cycle
               Lower Priority Areas: Appendices G and H
          Transport & Fate
               Lower Priority Areas: Appendices G and H
          Exposure, Uptake, and Dose
               Lower Priority Areas: Appendices G and H
          Impacts
               Lower Priority Areas: Appendices G and H
• Nanoscale Silver
     External Review Draft
     Final Case Study
          Exposure, Uptake and Dose
          Effects
• Ramazzini Institute